FDRdb: Fibrotic Disease-associated RNAome database, is an open and up-to-data online manually curated depository of RNAs alterations and high-throughput datasets about fibrotic diseases across various species. The current version of FDRdb documents 1950 associations between 912 RNAs and 92 fibrotic diseases in 8 species, manually collected from 1127 published literature, and collects information on 765 datasets of fibrotic diseases, including 624 RNA expression profiles, 32 methylation profiles and 108 sequencing datasets.

Fibrosis is a common pathological outcome because of the severe or repetitive tissue injury or the dysregulation of wound-healing repair. Fibrotic diseases are defined by the abnormal deposition of extracellular matrix, which can affect various organs such as lung, liver, kidney, heart and skin. Fibrotic diseases can lead to organ dysfunction and death.